报告嘉宾：何志明教授（美国工程院院士）
报告时间：3月20日（周四）下午14:00-15：50
报告地点：费彝民楼A-310
Abstract
In human disease, many molecular assemblies and pathways in the cellular network behave and interact aberrantly compared with how they act in a healthy state. Intricate cellular functions emerge from mutual interactions of a collection of signaling complexes and difficult to address by studying individual cellular components in isolation. The cellular network changes dynamically as it is subjected to external stimulations. The resultant responses of the bio-system are often not transparent as the result of this innate complexity. The most effective way to handle a problem of the magnitude and complexity as a human disease is to attack it on many fronts, such as by using combinatorial drug therapies. A multidisciplinary paradigm shift concept Feedback System Control (FSC) technology has been developed and can efficiently handle the agile adaptability of biological systems toward environmental stimuli. FSC can provide unprecedented control and insight into the dynamic nature of cellular behavior to enable directed cellular phenotypic and genotypic outcomes for transformative applications in Phenotypic personalized medicine.
Curriculum Vita
Dr. Chih-Ming Ho (http://ho.seas.ucla.edu/) received his Ph.D. from The Johns Hopkins University and holds the Ben Rich-Lockheed Martin Chair Professor in the UCLA School of Engineering. He was the Director of NIH supported Center for Cell Control (CCC) and NASA supported Institute for Cell Mimetic Space Exploration (CMISE). He served as the UCLA Associate Vice Chancellor for Research from 2001-2005.
Dr. Ho is known for his work in microfluidics, bio system technologies and turbulence. He is ranked by ISI as one of the top 250 most cited researchers worldwide in the entire engineering category. In 1997, Dr. Ho was inducted as a member of the National Academy of Engineering. In the next year, he was elected as an Academician of Academia Sinica. Dr. Ho holds 10 honorary professorships including the Einstein Professor of Chinese Academy of Sciences . He has delivered 18 named distinguished lectures and presented over 130 plenary/keynote talks in international conferences. Dr. Ho was elected Fellow of the American Institute of Medical and Biomedical Engineering, American Physical Society as well as American Institute of Aeronautics and Astronautics.